解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:BACKGROUND AND PURPOSE:Ipsilateral thalamic diaschisis (ITD) describes the reduction of thalamic function, metabolism, and perfusion resulting from a distant lesion of the ipsilateral hemisphere. Our aim was to evaluate the perfusion characteristics and clinical impact of ITD in acute middle cerebral artery stroke, whi...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.118.020698
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We evaluated the impact of a primary stroke center (PSC) destination policy in a major metropolitan city and used geographic modeling to evaluate expected changes for a comprehensive stroke center policy. METHODS:We identified suspected stroke emergency medical services encounters from 1/1/2004 ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.118.020691
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The majority of ischemic stroke patients receiving endovascular recanalization therapy (EVT) experience variable changes of neurological severities during the hyperacute period. We hypothesized that the National Institutes of Health Stroke Scale (NIHSS) score after EVT is a better prognostic fact...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.020587
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Neutrophil Extracellular Traps (NETs) are DNA extracellular networks decorated with histones and granular proteins produced by activated neutrophils. NETs have been identified as major triggers and structural factors of thrombosis. A recent study designated extracellular DNA threads from NETs as ...
journal_title:Stroke
pub_type: 临床试验,杂志文章
doi:10.1161/STROKEAHA.117.019896
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Attained height, an indicator of genetic potential and childhood growth environment, is inversely associated with stroke, but the mechanisms are poorly understood. We investigated whether childhood height and growth are associated with ischemic stroke (IS) and intracerebral hemorrhage (ICH). MET...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.019880
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:In acute ischemic stroke, fast and complete recanalization of the occluded vessel is associated with improved outcomes. We describe a novel measure for newer generation devices: the first pass effect (FPE). FPE is defined as achieving a complete recanalization with a single thrombectomy device pa...
journal_title:Stroke
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1161/STROKEAHA.117.020315
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Limited data exist on the performance of the revised Framingham Stroke Risk Score (R-FSRS) and the R-FSRS in conjunction with nontraditional risk markers. We compared the R-FSRS, original FSRS, and the Pooled Cohort Equation for stroke prediction and assessed the improvement in discrimination by ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.018928
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The ABC/2 method for calculating intracerebral hemorrhage (ICH) volume has been well validated. However, the formula, derived from the volume of an ellipse, assumes the shape of ICH is elliptical. We sought to compare the agreement of the ABC/2 formula with other methods through retrospective ana...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.016677
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Data are scarce on both stroke incidence rates and outcomes in Greece and in rural areas in particular. We performed a prospective population-based study evaluating the incidence of first-ever stroke in the Evros prefecture, a region of a total 147 947 residents located in North Eastern Greece. ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.019524
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Transient ischemic attack (TIA) initiates an ischemic cascade without resulting in frank infarction and, as such, represents a novel model to study the effects of this ischemic cascade and secondary neurodegeneration in humans. METHODS:Patients with suspected TIA underwent acute brain perfusion ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.019276
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Central autonomic dysfunction increases stroke morbidity and mortality. We aimed to investigate whether poststroke autonomic dysfunction graded by Ewing battery can predict clinical outcome. METHODS:In this prospective observational study, we assessed autonomic function of ischemic stroke patien...
journal_title:Stroke
pub_type: 临床试验,杂志文章
doi:10.1161/STROKEAHA.117.019312
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Elevated cardiac troponin is a marker of cardiac disease and has been recently shown to be associated with embolic stroke risk. We hypothesize that early elevated troponin levels in the acute stroke setting are more prevalent in patients with embolic stroke subtypes (cardioembolic and embolic str...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.019395
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Inflammatory mechanisms can exacerbate ischemic tissue damage and worsen clinical outcome in patients with stroke. Both αβ and γδ T cells are established mediators of tissue damage in stroke, and the role of dendritic cells (DCs) in inducing the early events of T cell activation and differentiati...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.019101
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The effect of statins on progression of carotid intima-media complex thickness (IMT) has been shown exclusively in nonstroke Western patients. This study aimed to determine the effect of low-dose pravastatin on carotid IMT in Japanese patients with noncardioembolic ischemic stroke. METHODS:This ...
journal_title:Stroke
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1161/STROKEAHA.117.018387
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Striatal GABAergic neuron is known as a key regulator in adult neurogenesis. However, the specific role of striatal GABAergic neuronal activity in the promotion of neurological recovery after ischemic stroke remains unknown. Here, we used optogenetic approach to investigate these effects and mech...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.019017
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Chinese patients largely experience acute ischemic stroke (AIS) because of large artery atherosclerosis rather than cardioembolism, and whether tirofiban is safe and effective in these patients treated with endovascular thrombectomy (ET) is unknown. This study evaluated the safety and efficacy of...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.019193
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The mortality and morbidity after aneurysmal subarachnoid hemorrhage has improved because of better diagnosis, early treatment to secure the aneurysm, and better management of disease-specific complications. With these improvements in care, it is not clear if the previously identified independent...
journal_title:Stroke
pub_type: 杂志文章,多中心研究
doi:10.1161/STROKEAHA.117.017777
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The visual analogue scale is a self-reported, validated tool to measure quality of life (QoL). Our purpose was to determine whether baseline QoL predicted strokes in the ALLHAT study (Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial) and evaluate determinants of poststr...
journal_title:Stroke
pub_type: 杂志文章,随机对照试验
doi:10.1161/STROKEAHA.117.016062
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We aimed to evaluate the efficacy of remote ischemic conditioning (RIC) in patients with cerebral small-vessel disease. METHODS:Thirty patients with cerebral small-vessel disease-related mild cognitive impairment were enrolled in this prospective, randomized controlled study for 1 year. Besides ...
journal_title:Stroke
pub_type: 杂志文章,随机对照试验
doi:10.1161/STROKEAHA.117.017691
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Despite the social, health, and economic burdens associated with cognitive impairment poststroke, there is considerable uncertainty about the types of interventions that might preserve or restore cognitive abilities. The objective of this systematic review and meta-analysis was to evaluate the ef...
journal_title:Stroke
pub_type: 杂志文章,meta分析,评审
doi:10.1161/STROKEAHA.117.017319
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Perioperative strokes (POS) are rare but serious complications for which mechanical thrombectomy could be beneficial. We aimed to compare the technical results and patients outcomes in a population of POS versus non-POS (nPOS) treated by mechanical thrombectomy. METHODS:From 2010 to 2017, 25 pat...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.018033
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Ischemic stroke patients often have intracranial atherosclerosis (ICAS), despite heterogeneity in the cause of stroke. We tested the hypothesis that ICAS burden can independently reflect the risk of long-term vascular outcome. METHODS:This was a retrospective cohort study analyzing data from a p...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.017806
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:White matter (WM) is less vulnerable to ischemia than gray matter. In ischemic stroke caused by acute large-vessel occlusion, successful recanalization might therefore sometimes selectively salvage the WM, leading to infarct patterns confined to gray matter. This study examines occurrence, determ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.017903
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Cerebral edema (CED) is a severe complication of acute ischemic stroke. There is uncertainty regarding the predictors for the development of CED after cerebral infarction. We aimed to determine which baseline clinical and radiological parameters predict development of CED in patients treated with...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.018223
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Although the mechanisms that contribute to intracranial aneurysm (IA) formation and rupture are not totally elucidated, inflammation and matrix remodeling are incriminated. Because tPA (tissue-type plasminogen activator) controls both inflammatory and matrix remodeling processes, we hypothesized ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.017305
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Malignant cerebellar edema (MCE) is a life-threatening complication of acute ischemic stroke that requires timely diagnosis and management. Aim of this study was to identify imaging predictors in initial multiparametric computed tomography (CT), including whole-brain CT perfusion (WB-CTP). METHO...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.018237
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Dysphagia is a common stroke symptom and leads to serious complications such as aspiration and pneumonia. Early dysphagia screening can reduce these complications. In many hospitals, dysphagia screening is performed by speech-language therapists who are often not available on weekends/holidays, w...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.018157
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Multicenter clinical trials attempt to select sites that can move rapidly to randomization and enroll sufficient numbers of patients. However, there are few assessments of the success of site selection. METHODS:In the CREST-2 (Carotid Revascularization and Medical Management for Asymptomatic Car...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.016976
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Subarachnoid hemorrhage (SAH) is associated with a temporal pattern of stroke incidence. We hypothesized that natural oscillations in gene expression controlling circadian rhythm affect the severity of neuronal injury. We moreover predict that heme oxygenase-1 (HO-1/Hmox1) and its product carbon ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.116.016165
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The aim of this study is to assess whether the PHASES score allows to (1) match decisions taken by multidisciplinary team whether to observe or intervene, (2) classify patients being diagnosed with a ruptured versus unruptured intracranial aneurysm (UIA), and (3) discriminate patients at low risk...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.017391
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Several markers of poststroke cognitive impairment have been reported. The role of brain cortical volume remains uncertain. The aim of this study was to evaluate the influence of brain cortical volume on cognitive outcomes using a voxel-based morphometry approach in subjects without prestroke dem...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.017646
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Statin use may be associated with improved outcome in intracerebral hemorrhage patients. However, the topic remains controversial. Our analysis examined the effect of prior, continued, or new statin use on intracerebral hemorrhage outcomes using the ERICH (Ethnic/Racial Variations of Intracerebra...
journal_title:Stroke
pub_type: 杂志文章,多中心研究
doi:10.1161/STROKEAHA.117.017358
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We aimed to describe the frequency and characteristics of acute ischemic stroke and transient ischemic attacks presenting predominantly with amnesia (ischemic amnesia) and to identify clinical clues for differentiating them from transient global amnesia (TGA). METHODS:We retrospectively analyzed...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.017420
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Thrombolysis rates among minor stroke (MS) patients are increasing because of increased recognition of disability in this group and guideline changes regarding treatment indications. We examined the association of delays in door-to-needle (DTN) time with stroke severity. METHODS:We performed a r...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.017386
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Interhospital transfer is a critical component in the treatment of acute anterior circulation large vessel occlusive stroke transferred for mechanical thrombectomy. Real-world data for benchmarking and theoretical modeling are limited. We sought to characterize transfer workflow from primary stro...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.017235
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The American Heart Association/American Stroke Association and Department of Health Stroke Coverdell Program convened a stakeholder meeting in upstate NY to develop recommendations to enhance stroke systems for acute large vessel occlusion. METHODS:Prehospital, hospital, and Department of Health...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.017412
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The CHA2DS2-VASc stroke score (congestive heart failure, hypertension, age ≥75 (doubled), diabetes mellitus, prior stroke or transient ischemic attack (doubled), vascular disease, age 65-74, female) is used in most guidelines for risk stratification in atrial fibrillation (AF), but most data for ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.016926
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The influence of dietary protein intake on stroke risk is an area of interest. We investigated the association between dietary protein intake and stroke risk in Japanese, considering sources of protein. METHODS:A total of 2400 subjects aged 40 to 79 years were followed up for 19 years. Dietary p...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.116.016059
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The majority of patients enrolled in SWIFT PRIME trial (Solitaire FR With the Intention for Thrombectomy as Primary Endovascular Treatment for Acute Ischemic Stroke) had computed tomographic perfusion (CTP) imaging before randomization; 34 patients were randomized after magnetic resonance imaging...
journal_title:Stroke
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1161/STROKEAHA.117.016669
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The Emergency Medical Services field triage to stroke centers has gained considerable complexity with the recent demonstration of clinical benefit of endovascular treatment for acute ischemic stroke. We sought to describe a new smartphone freeware application designed to assist Emergency Medical ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.116.016026
更新日期:2017-05-01 00:00:00